Toward a Science of Consciousnessmarks the first major gathering -- a landmark event -- devoted entirely to unlocking the mysteries of consciousness.

When and where did consciousness emerge in the course of evolution? Did it happen as recently as the past million years, for example concomitant with language or tool making in humans or primates? Or did consciousness arrive somewhat earlier, with the advent of mammalian neocortex 200 million years ago (Eccles, 1992)? At the other extreme, is primitive consciousness a property of even simple unicellular organisms of several billion years ago (e.g. as suggested by Margulis and Sagan, 1995)? Or did consciousness (...) appear at some intermediate point, and if so, where and why? Whenever it first occurred, did consciousness alter the course of evolution? (shrink)

This volume presents a selection of invited papers from the second conference, held in April 1996.

Quantum aspects of brain activity and the role of consciousness. Proceedings of the National ... Casti, JL 1996. Confronting science's logical limits. ...

In "Brainshy: Non-neural theories of conscious experience," (this volume) Patricia Churchland considers three "non-neural" approaches to the puzzle of consciousness: 1) Chalmers' fundamental information, 2) Searle's "intrinsic" property of brain, and 3) Penrose-Hameroff quantum phenomena in microtubules. In rejecting these ideas, Churchland flies the flag of "neuralism." She claims that conscious experience will be totally and completely explained by the dynamical complexity of properties at the level of neurons and neural networks. As far as consciousness goes, neural network firing patterns (...) triggered by axon-to-dendrite synaptic chemical transmissions are the fundamental correlates of consciousness. There is no need to look elsewhere. (shrink)

_Sonoran Desert, Stuart Hameroff and Alwyn Scott awoke from their_ _siestas to take margaritas in the shade of a ramada. On a nearby_ _table, a tape recorder had accidentally been left on and the following_ _is an unedited transcript of their conversation._.

What is consciousness? Some philosophers have contended that ‘qualia’, or an experiential medium from which consciousness is derived, exists as a fundamental component of reality. Whitehead, for example, described the universe as being comprised of ‘occasions of experience’. To examine this possibility scientifically, the very nature of physical reality must be re-examined. We must come to terms with the physics of space-time -- as is described by Einstein's general theory of relativity -- and its relation to the fundamental theory of (...) matter -- as described by quantum theory. This leads us to employ a new physics of objective reduction: OR which appeals to a form of ‘quantum gravity’ to provide a useful description of fundamental processes at the quantum/classical borderline . Within the OR scheme, we consider that consciousness occurs if an appropriately organized system is able to develop and maintain quantum coherent superposition until a specific ‘objective’ criterion is reached; the coherent system then self-reduces . We contend that this type of objective self-collapse introduces non-computability, an essential feature of consciousness. OR is taken as an instantaneous event -- the climax of a self-organizing process in fundamental space-time -- and a candidate for a conscious Whitehead-like ‘occasion’ of experience. How could an OR process occur in the brain, be coupled to neural activities, and account for other features of consciousness? We nominate an OR process with the requisite characteristics to be occurring in cytoskeletal microtubules within the brain's neurons. (shrink)

Proposals for quantum computation rely on superposed states implementing multiple computations simultaneously, in parallel, according to quantum linear superposition (e.g., Benioff, 1982; Feynman, 1986; Deutsch, 1985, Deutsch and Josza, 1992). In principle, quantum computation is capable of specific applications beyond the reach of classical computing (e.g., Shor, 1994). A number of technological systems aimed at realizing these proposals have been suggested and are being evaluated as possible substrates for quantum computers (e.g. trapped ions, electron spins, quantum dots, nuclear spins, etc., (...) see Table 1; Bennett, 1995; and Barenco, 1995). The main obstacle to realization of quantum computation is the problem of interfacing to the system (input, output) while also protecting the quantum state from environmental decoherence. If this problem can be overcome, then present day classical computers may evolve to quantum computers. (shrink)

The paper begins with a general introduction to the nature of human consciousness and outlines several different philosophical approaches. A critique of traditional reductionist and dualist positions is offered and it is suggested that consciousness should be viewed as an emergent property of physical systems. However, although consciousness has its origin in distributed brain processes it has macroscopic properties - most notably the `unitary sense of self', non-deterministic free will, and non-algorithmic `intuitive' processing - which can best be described by (...) quantum-mechanical principles. (shrink)

_Figure 1. Dendrites and cell bodies of schematic neurons connected by dendritic-dendritic gap junctions form a laterally connected input_ _layer (“dendritic web”) within a neurocomputational architecture. Dendritic web dynamics are temporally coupled to gamma synchrony_ _EEG, and correspond with integration phases of “integrate and fire” cycles. Axonal firings provide input to, and output from, integration_ _phases (only one input, and three output axons are shown). Cell bodies/soma contain nuclei shown as black circles; microtubule networks_ _pervade the cytoplasm. According to the (...) Orch OR theory, gamma EEG-synchronized integration phases include quantum computations in_ _microtubule networks which culminate with conscious moments. Insert closeup shows a gap junction through which microtubule quantum_ _states entangle among different neurons, enabling macroscopic quantum states in dendritic webs extending throughout cortex and other_ _brain regions._. (shrink)

Social justice needs a home, a place where it can be found, especially for young people growing up in fragmented and increasingly inequitable societies. Community youth arts organizations have secured a certain prominence in this context over the past three decades and are now part of the urban infrastructures that shape connected learning networks in highly industrialized nations. In this capacity, youth arts organizations regularly engage a language and aesthetics of authenticity and trust as part of how they call out, (...) represent and make a home for children and youth. This paper examines how authenticity in youth culture and youth cultural expression is negotiated by arts organizations and how organizations locate their own trustworthiness as allies of young people through the curation of online media archives. The analysis draws on the internet media archives of two youth arts organizations in Canada’s largest English-speaking cities. The Oasis Skateboard Factory in Toronto, ON is an extension program of the Toronto District School Board that enables participants to create their own brands and learn to run a skateboard or professional design business. ReelYouth started in Vancouver in 2005 as a community media empowerment project, and now delivers programs across Canada and internationally.The claims to youth authenticity articulated in each media archive reveal how authenticity and trust are negotiated ideologically by each organization and how organizations mark their ontological status, as a home from which young people can think and respond to an unjust world. I examine how youth authenticity is produced by analyzing how discourses of youth identity, connection and trust are deployed across each archive. Whilst showcasing how authenticity is negotiated by each group, I show how the production of authenticity discourses by OSF and ReelYouth simultaneously convey a deeper reality: the way youth arts groups operate as care structures that offer ontological security, and places of increasing “awareness of previously unnoticed interconnections” for youth. In this way, they operate as sites of border work, places of routing from which the work of social justice can be borne. (shrink)

Age-old battle lines over the puzzling nature of mental experience are shaping a modern resurgence in the study of consciousness. On one side are the long-dominant "physicalists" who view consciousness as an emergent property of the brain's neural networks. On the alternative, rebellious side are those who see a necessary added ingredient: proto-conscious experience intrinsic to reality, perhaps understandable through modern physics (panpsychists, pan-experientialists, "funda-mentalists"). It is argued here that the physicalist premise alone is unable to solve completely the difficult (...) issues of consciousness and that to do so will require supplemental panpsychist/pan-experiential philosophy expressed in modern physics. In one scheme proto-conscious experience is a basic property of physical reality accessible to a quantum process associated with brain activity. The proposed process is Roger Penrose's "objective reduction" (OR), a self-organizing "collapse" of the quantum wave function related to instability at the most basic level of space-time geometry. In the Penrose- Hameroff model of "orchestrated objective reduction" (Orch OR), OR quantum computation occurs in cytoskeletal microtubules within the brain's neurons. The basic thesis is that consciousness involves brain activities coupled to a self-organizing ripples in fundamental reality. (shrink)

feelings (brainstem, limbic system). The best scientific synchrony and consciousness.21,27 Anesthesiology, V 105, No 2, Aug 2006.

What is consciousness? Conventional approaches see it as an emergent property of complex interactions among individual neurons; however these approaches fail to address enigmatic features of consciousness. Accordingly, some philosophers have contended that "qualia," or an experiential medium from which consciousness is derived, exists as a fundamental component of reality. Whitehead, for example, described the universe as being composed of "occasions of experience." To examine this possibility scientifically, the very nature of physical reality must be re-examined. We must come to (...) terms with the physics of spacetime-as described by Einstein's general theory of relativity, and its relation to the fundamental theory of matter-as described by quantum theory. Roger Penrose has proposed a new physics of objective reduction: "OR," which appeals to a form of quantum gravity to provide a useful description of fundamental processes at the quantum/classical borderline.hz Within the OR scheme, we consider that consciousness occurs if an appropriately organized system is able to develop and maintain quantum coherent superposition until a specific "objective" criterion (a threshold related to quantum gravity) is reached; the coherent system then self-reduces (objective reduction: OR). We contend that this type of objective self-collapse introduces non-computability, an essential feature of consciousness which distinguishes our minds from classical computers. Each OR is taken as an instantaneous event-the climax of a self-organizing process in fundamental spacetime-and a candidate for a conscious Whitehead "occasion of experience." How could an OR process occur in the brain, be coupled to neural activities, and account for other features of consciousness? We nominate a quantum computational OR process with the requisite characteristics to be occurring in cytoskeletal microtubules within the brain's neurons. In this model, quantum-superposed states develop in microtubule subunit proteins ("tubulins") within certain brain neurons, remain coherent, and recruit more superposed tubulins until a mass-time-energy threshold (related to quantum gravity) is reached.. (shrink)

1. Introduction: The problems of time and consciousness What is time? St. Augustine remarked that when no one asked him, he knew what time was; however when someone asked him, he did not. Is time a process which flows? Is time a dimension in which processes occur? Does time actually exist? The notion that time is a process which "flows" directionally may be illusory (the "myth of passage") for if time did flow it would do so in some medium or (...) vessel (e.g. minutes per what?) [1]. But if time is a dimension in which processes occurred, e.g. as one component of a 4 dimensional spacetime, then why would processes occur unidirectionally in time? Yet we perceive time as an orderly, unidirectional process. An alternative explanation is that time does not exist as either a process or dimension, but that reality is a collage of discrete, disconnected and haphazardly arranged configurations of the universe, e.g. as described in Julian Barbour's "The end of time" [2]. In this view our perception of a unidirectional flow of time occurs because each moment, or "Now" as Barbour terms them, involves memory of other conceptually relevant moments, and the orderly flow of time is an illusion. Barbour's deconstruction of time contrasts the Newtonian reality of objects moving deterministically through 4 dimensional spacetime. Newton's contemporary (and rival) Leibniz [3] viewed the world in a manner consistent with Barbour (and with Mach's principle that the spatiotemporal structure of the universe is dependent on the distribution of mass, a foundation of Einstein's general relativity). According to Leibniz the world is to be understood not as matter/mass moving in a framework of space and time, but of more fundamental snapshot-like entities that momentarily fuse space and matter into single possible arrangements or configurations of the entire universe. Such configurations, which can be fabulously rich and complex considering the vastness of the universe, are the ultimate "things" of reality, which Leibniz termed "monads".. (shrink)

The theory suggests that quantum computations in brain neuronal dendritic-somatic microtubules regulate axonal firings to control conscious behavior. Within microtubule subunit proteins, collective dipoles in arrays of contiguous amino acid electron clouds enable suitable for topological dipole able to physically represent cognitive values, for example, those portrayed by Pothos & Busemeyer (P&B) as projections in abstract Hilbert space.

_dualism_ (consciousness lies outside knowable science), _emergence_ (consciousness arises as a novel property from complex computational dynamics in the brain), and some form of _panpsychism_, _pan-protopsychism, or pan-experientialism_ (essential features or precursors of consciousness are fundamental components of reality which are accessed by brain processes). In addition to 1) the problem of subjective experience, other related enigmatic features of consciousness persist, defying technological and philosophical inroads. These include 2) the “binding problem”—how disparate brain activities give rise to a unified sense (...) of “self” or unified conscious content. Temporal synchrony—brain-wide coherence of neural membrane electrical activities—is often assumed to accomplish binding, but _what_ is being synchronized? What is being coherently bound? Another enigmatic feature is 3) the transition from pre-conscious processes to consciousness itself. Most neuroscientists agree that consciousness is the “tip of an iceberg”, that the vast majority of brain activities is. (shrink)

Grush and Churchland (1995) attempt to address aspects of the proposal that we have been making concerning a possible physical mechanism underlying the phenomenon of consciousness. Unfortunately, they employ arguments that are highly misleading and, in some important respects, factually incorrect. Their article ‘Gaps in Penrose’s Toilings’ is addressed specifically at the writings of one of us (Penrose), but since the particular model they attack is one put forward by both of us (Hameroff and Penrose, 1995; 1996), it is appropriate (...) that we both reply; but since our individual remarks refer to different aspects of their criticism we are commenting on their article separately. The logical arguments discussed by Grush and Churchland, and the related physics are answered in Part l by Penrose, largely by pointing out precisely where these arguments have already been treated in detail in Shadows of the Mind (Penrose, 1994). In Part 2, Hameroff replies to various points on the biological side, showing for example how they have seriously misunderstood what they refer to as ‘physiological evidence’ regarding to effects of the drug colchicine. The reply serves also to discuss aspects of our model ‘orchestrated objective reduction in brain microtubules – Orch OR’ which attempts to deal with the serious problems of consciousness more directly and completely than any previous theory. (shrink)

A theoretical approach relying on quantum computation in microtubules within neurons can potentially resolve the enigmatic features of visual consciousness, but raises other questions. For example, how can delicate quantum states, which in the technological realm demand extreme cold and isolation to avoid environmental ‘decoherence’, manage to survive in the warm, wet brain? And if such states could survive within neuronal cell interiors, how could quantum states grow to encompass the whole brain? We present a physiological model for visual consciousness (...) that can accommodate brain-wide quantum computation according to the Penrose–Hameroff ‘Orch OR’ model. In this view, visual consciousness occurs as a series of several-hundred-millisecond epochs, each comprising ‘crescendo sequences’ of quantum computations occurring at ∼40 Hz. (shrink)

Mechanisms that contribute to perceptual processing dysfunction in schizophrenia were examined by Phillips & Silverstein, and formulated as involving disruptions in both local and higher-level coordination of signals. We agree that dysfunction in the coordination of cognitive functions (disconnection) is also indicated for many of the linguistic processing deficits documented for schizophrenia. We suggest, however, that it may be necessary to add a timing mechanism to the theoretical account.

Thomas & Karmiloff- Smith ’ argument that the Residual Normality assumption is not valid for developmental disorders has implications for models of cognition in schizophrenia, a disorder that may involve a neurodevelopmental pathogenesis. A limiting factor for such theories is the lack of understanding about the nature of the cognitive system. Moreover, it is unclear how the proposal that modularization emerges from developmental processes would change that fundamental question.

Strong evidence shows that exposure and engagement with the natural world not only improve human wellbeing but can also help promote environmentally friendly behaviors. Human-nature relationships are at the heart of global agendas promoted by international organizations including the World Health Organization’s “One Health” and the United Nations “Ocean Decade.” These agendas demand collaborative multisector interdisciplinary efforts at local, national, and global levels. However, while global agendas highlight global goals for a sustainable world, developing science that directly addresses these agendas (...) from design through to delivery and outputs does not come without its challenges. In this article, we present the outcomes of international meetings between researchers, stakeholders, and policymakers from the United Kingdom and Brazil. We propose a model for interdisciplinary work under such global agendas, particularly the interface between One Health and the UN Ocean Decade and identify three priority research areas closely linked to each other: human-nature connection, conservation-human behavior, and implementation strategies. We also discuss a number of recommendations for moving forward. (shrink)

Scholars and practitioners across domains are increasingly concerned with algorithmic transparency and opacity, interrogating the values and assumptions embedded in automated, black-boxed systems, particularly in user-generated content platforms. I report from an ethnography of infrastructure in Wikipedia to discuss an often understudied aspect of this topic: the local, contextual, learned expertise involved in participating in a highly automated social–technical environment. Today, the organizational culture of Wikipedia is deeply intertwined with various data-driven algorithmic systems, which Wikipedians rely on to help manage (...) and govern the “anyone can edit” encyclopedia at a massive scale. These bots, scripts, tools, plugins, and dashboards make Wikipedia more efficient for those who know how to work with them, but like all organizational culture, newcomers must learn them if they want to fully participate. I illustrate how cultural and organizational expertise is enacted around algorithmic agents by discussing two autoethnographic vignettes, which relate my personal experience as a veteran in Wikipedia. I present thick descriptions of how governance and gatekeeping practices are articulated through and in alignment with these automated infrastructures. Over the past 15 years, Wikipedian veterans and administrators have made specific decisions to support administrative and editorial workflows with automation in particular ways and not others. I use these cases of Wikipedia’s bot-supported bureaucracy to discuss several issues in the fields of critical algorithms studies; critical data studies; and fairness, accountability, and transparency in machine learning—most principally arguing that scholarship and practice must go beyond trying to “open up the black box” of such systems and also examine sociocultural processes like newcomer socialization. (shrink)

The proposal that the hippocampus is important for the encoding of episodic information, but not familiarity-based recognition, is incompatible with the available data. An alternative way to think about functional specialization within the medial temporal lobe memory system is suggested, based on neuroanatomy.

This collection of original essays, by some of the best known contemporary criminal law theorists, tackles a range of issues about the criminal law's 'special part' - the part of the criminal law that defines specific offences. One of its aims is to show the importance, for theory as well as for practice, of focusing on the special part as well as on the general part which usually receives much more theoretical attention. Some of the issues covered concern the proper (...) scope of the criminal law, for example how far should it include offences of possession, or endangerment? If it should punish only wrongful conduct, how can it justly include so-called 'mala prohibita', which are often said to involve conduct that is not wrongful prior to its legal prohibition? Other issues concern the ways in which crimes should be classified. Can we make plausible sense, for instance, of the orthodox distinction between crimes of basic and general intent? Should domestic violence be defined as a distinct offence, distinguished from other kinds of personal violence? Also examined are the ways in which specific offences should be defined, to what extent those definitions should identify distinctive types of wrongs, and the light that such definitional questions throw on the grounds and structures of criminal liability. Such issues are discussed in relation not only to such crimes as murder, rape, theft and other property offences, but also in relation to offences such as bribery, endangerment and possession that have not traditionally been subjects for in depth theoretical analysis. (shrink)

25 leading contemporary theorists of criminal law tackle a range of foundational issues about the proper aims and structure of the criminal law in a liberal democracy. The challenges facing criminal law are many. There are crises of over-criminalization and over-imprisonment; penal policy has become so politicized that it is difficult to find any clear consensus on what aims the criminal law can properly serve; governments seeking to protect their citizens in the face of a range of perceived threats have (...) pushed the outer limits of criminal law and blurred its boundaries. To think clearly about the future of criminal law, and its role in a liberal society, foundational questions about its proper scope, structure, and operations must be re-examined. What kinds of conduct should be criminalized? What are the principles of criminal responsibility? How should offences and defences be defined? The criminal process and the criminal trial need to be studied closely, and the purposes and modes of punishment should be scrutinized. Such a re-examination must draw on the resources of various disciplines-notably law, political and moral philosophy, criminology and history; it must examine both the inner logic of criminal law and its place in a larger legal and political structure; it must attend to the growing field of international criminal law, it must consider how the criminal law can respond to the challenges of a changing world.Topics covered in this volume include the question of criminalization and the proper scope of the criminal law; the grounds of criminal responsibility; the ways in which offences and defences should be defined; the criminal process and its values; criminal punishment; the relationship between international criminal law and domestic criminal law. Together, the essays provide a picture of the exciting state of criminal law theory today, and the basis for further research and debate in the coming years. (shrink)

While innovations have fostered the mass production of food at low costs, there are externalities or side effects associated with high-volume food processing. We focus on foodborne illness linked to two commodities: ground beef and bagged salad greens. In our analysis, we draw from the concepts of risk, reflexive modernization, and techniques of ethical neutralization. For each commodity, we find that systems organized for industrial goals overlook how production models foster cross-contamination and widespread outbreaks. Responses to outbreaks tend to rely (...) on technological fixes, which do not constitute the reflexive change needed to holistically and effectively address foodborne illness in the long term. We contend that powerful anti-reflexivity movements resist calls for reform and successfully maintain industrial goals and organization. Actions that thwart changes in agrifood systems to better protect consumers are unethical, yet they continue to be successful. We argue that specific techniques of ethical neutralization play an important part in their success. Research on anti-reflexivity and techniques of neutralization will serve to further expose the ethical issues associated with the industrial agrifood system and foster new guiding principles and organizational designs for food production. (shrink)

Youths with disruptive behavior disorders and psychopathic traits showed reduced amygdala responses to fearful expressions under low attentional load but no indications of increased recruitment of regions implicated in top- down attentional control. These findings suggest that the emotional deficit observed in youths with disruptive behavior disorders and psychopathic traits is primary and not secondary to increased top- down attention to nonemotional stimulus features.